Levofloxacin hemihydrate helps to fight the bacteria and is belongs to the category of antibiotic.
It is actively killing gram-positive and gram-negative bacteria
It is optically active and is exist in R form.
Upper respiratory Tract
Lower respiratory tract
Cystic fibrosis
Cellulitis
Community acquire pneumonia
Levofloxacin inhibits the activity of enzyme DNA gyrase and topoisomerase-4. DNA gyrase causes the negative supercoiling during DNA replication.
Absorption- It is absorbed orally
Protein Binding- It mainly bound to albumin
Metabolism- It is metabolized in the liver
Excretion- It is excreted via urine
Constipation
Diarrhoea
Difficulty in sleeping
Dizziness
Headache
Contraindicated in Diabetes
Contraindicated in G6PD deficiency
Warfarin
Sucralfate
Didanosine
Aluminium
Iron
Zinc
| Levofloxacin | 250 mg |