Levocetirizine belongs to the histamine receptor antagonist and has greater affinity for the histamine-1 receptors. It is generally known as R- enantiomer of levocetirizine. It is used to treat allergic symptoms.
Chronic idiopathic urticaria
Seasonal allergic rhinitis
Perennial allergic rhinitis
Levocetirizine inhibits the histamine receptors more likely H1 receptors and blocks the activity of histamine such as smooth muscle contraction. increased permeability of vascular endothelium, histidine uptake in basophils and stimulation of cough receptors.
Absorption- It is absorbed orally
Protein Binding-It is 91% bound to plasma proteins
Metabolism-It undergoes O-dealkylation
Excretion-It is excreted unchanged via urine
Drowsiness
Tiredness
Dry mouth
Fever
Cough
Contraindicated in people with hypersensitivity
Contraindicated in Asthma
Contraindicated in renal disease.
Clobazam
Hyaluronidase
Ritonavir
| Levocetirizine | 5 mg |