This composition contains Cefoperazone sodium and Sulbactum sodium which are used in combination to prevent the formation of bacterial protective covering outside bacteria which is necessary for the survival of bacteria.
Respiratory tract infections
Peritonitis
Skin infections
Endometritis
Urinary tract infections
Cefoperazone binds to penicillin binding protein which is present in the bacteria and thus inhibits the cell wall synthesis process and further cell wall lysis is mediated by autolysin enzymes.
Sulbactam inhibits the beta-lactamase enzyme of the bacteria which is responsible for the development of resistance and prevents the reduction in activity of bacteria.
Cefoperazone-
It is absorbed orally
It shows 93% protein binding
It is excreted mainly via urine
Sulbactam-
It is absorbed orally
It shows 38% serum proteins binding
It is excreted via urine
Common side effects of the injection includes:
Diarrhoea
Anemia
Allergic reaction
Contraindicated in people with bleeding disorders
Budesonide
Valproic acid
Tramadol
Metronidazole
Ipratropium
| Cefoperazone Sodium IP | 500 mg |
| Sulbactam Sodium USP | 500 mg |